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Initial side effects like nausea and diarrhea appear similar to injectable GLP-1s, but ongoing surveillance through Phase 4 studies is vital
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Officials say such mistakes can significantly increase health risks
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Nausea ranged from 26.5% (TRANSCEND-T2D-1) to 43% (TRIUMPH-4)
Subcutaneous semaglutide or oral empagliflozin was initiated non-randomly at the clinicians discretion, considering the need for treatment intensification and weight loss, as well as comorbidities (e.g., obesity with body mass index over 35 kg/m 2 , heart failure), contraindications (e.g., pancreatitis, kidney failure), and patient preferences
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